Seth’s blog

A successor to Medical Hypotheses, called Hypotheses in the Life Sciences, will be edited by William Bains and published by Buckingham University Press (BUP).

ROBERTS Does BUP hope to eventually make money from the successor journal? Or do they merely hope the subsidy required will decrease with time?

WILLIAM BAINS BUP is a small operation, and does not have the resources to subsidize Hypotheses in the Life Sciences beyond its start-up stage, so we hope to make enough money to break even fairly soon. Ultimately the aim is to be profitable. I for one am determined to put scientific quality first, and I have emphasized to BUP that I only want the journal to grow (and hence generate more revenue) when the quality of submissions allows it.

ROBERTS What led BUP to decide to publish the new journal?

BAINS I think a combination of similarity in philosophy and being in the right place at the right time. They thought it was an exciting project which would both raise their profile (in a good way) and make them money. Buckingham University is the UK’s only private university, and as such takes a heterodox, even iconoclastic view towards what the academic establishment says is writ in stone. The Chancellor has a robust approach to academic and individual freedom. So a journal trying to do something rather new, enabling those with good ideas but little power to be heard, fitted with their approach.  For me, an added advantage is that I deal directly with the man at the top. There are no intermediate layers of management to take decisions about the journal, and we discuss everything from philosophy to web page design. This is the sort of immediacy you do not get with a big publisher.

Part 1 (Bruce Charlton). Bioscience Hypotheses, a similar journal founded by Bains.

A successor to Medical Hypotheses, titled Hypotheses in the Life Sciences, will soon be published. I asked Bruce Charlton and William Bains, the founder of the new journal, about the economics of the situation.

ROBERTS Did Medical Hypotheses make money for Elsevier? How much did it cost to run per year (leaving aside time contributed by you and the editorial board)? How much of that did Elsevier pay?

BRUCE CHARLTON  Medical Hypotheses did for sure make money for Elsevier - but I was never allowed to see the accounts. (more…)

A writer for UC Berkeley media relations wanted to interview me for this press release about the Tsinghua Psychology department. I said I’d blogged a lot about Tsinghua but she said she wanted “fresh quotes”. So I wrote this:

Why did you decide to take this opportunity [become a professor at Tsinghua]?

Partly because I wanted to write more books — in addition to The Shangri-La Diet — and this job would let me, because I only teach one semester per year. Partly because I thought the undergraduates would be brilliant. Partly because I thought living in Beijing would be fascinating.

What have you learned/discovered?

How talented the students are. To get into Tsinghua as an undergraduate, you have to score extremely well on a nationwide test. Oh, so they’re bookish? Not quite. A month ago I went to a talent show put on by biomedical-engineering majors. One act was five girls dancing. After a few minutes someone told me that three of the girls were boys. I hadn’t noticed. It was really hard to tell.

Influenced by Mulan, perhaps.

Alexandra Carmichael is one of the founders of CureTogether.com, whom I met at a Quantified Self meeting last year. A few days ago, she left an interesting comment on one of my posts:

I practice random acts of kindness, with a goal of helping at least 10 people a day (and at least 1 person I don’t know). I find this helps my mood toward the end of the day, when it is most likely to fall - no matter what else has happened that day, at least I’ve helped 10 people.

I asked her about it:

SETH Where did the idea come from?

ALEXANDRA It goes all the way back to my grandparents being Scout leaders - I was never in the Scouts myself but I observed how helpful and supportive they always were. Then during my university years when I was forming my life philosophy, I got to attend an incredible lecture by Jane Goodall. Her organization Roots & Shoots inspires people around the world to give back to the earth, animals, and people around them, with her amazing presence and the quote “Every individual can make a difference.” Service learning is also one of the things we thread into homeschooling our two daughters, along with design, simple living, and non-violent communication.

The specific goal of helping 10 people a day started last summer during a goal-setting weekend. I was curious to see if formalizing and quantifying something I had been doing in a fuzzier way would make a difference in my life, if measuring acts of kindness would result in an increased number of acts, or more friends, or help me with my chronic depression - plus I love quantifying things! I don’t find it necessary to actually record how many people I help in a day, but I keep a rough running tally in my head as I go through the day to make sure it’s at least 10 - my kids like to help with this count too.

SETH What are some examples of these acts?

ALEXANDRA I do a lot of different things. If I get extra free tickets to events or conferences, I will pass them along to people who I think would love to go; I will offer to take a picture of a tourist family where one person inevitably gets left out behind the camera; I will connect people who I think would benefit from knowing each other; I will take two hours to listen and hug and support a child who is having a hard time learning a new skill; I will answer a newbie entrepreneur’s questions about how to get started in business or help them spread their message; I will help coordinate gatherings that I believe in (such as Quantified Self); I will hold the door for someone. It can be anything really, no matter how small.

SETH How have people reacted when you tell them about this?

ALEXANDRA The most frequent reaction is “That sounds too challenging to do every day - 10 people? Why not 1 or 2?” The second most frequent reaction is “You are inspiring me to make positive changes in my own life.” My answer to both is “I love helping people!”

SETH What have you learned?

ALEXANDRA if you help people, without wanting anything in return, you get help when you need it - often surprising help, and often more than you gave. I learned that helping people seems to make them like you more, so my number of online friends has skyrocketed (1500 on Twitter, 800 on Facebook, 500 on LinkedIn) - but close “in person” friends I choose to limit to a handful because of my tendency to get overwhelmed by frequent or shallow social situations. I learned that helping people does help with depression, because (a) you have something else to focus on outside of yourself and (b) you go through the day with an expectant air of wonder at who will be the next person you can help. I also learned that helping 10 people a day is really not a lot, and I often wind up helping 20 or more people in a day. Of course, this is only from my perspective - I can’t guarantee that all of these people actually feel helped, I just know that I tried to help.

SETH When you say “if you help people, without wanting anything in return, you get help when you need it - often surprising help, and often more than you gave” I’m not sure I understand. Can you give some examples?

ALEXANDRA It’s not so much that the people I help help me in return, but more that by spreading goodwill and being tuned in to what others need, I also became more aware of my own needs and started to feel a greater sense of self-worth, like I deserved to have my needs met. This is not something I was taught growing up, and I went through two bouts of major postpartum depression without asking for or getting the support I needed. I feel much more open about my needs now, which perhaps makes it easier for others to help me. So the change was more in me than in others.

In terms of specific examples, when I learned that I have a Tourette’s spectrum disorder, and tweeted that, I made an incredible new friend who has been through similar neurological issues, and who in our conversations of support and empathy has helped me more than I can ever thank him for. Also, when I decided to find some consulting work to support my family while we build CureTogether, a very welcoming door opened (soon to be made public), and offered me basically a dream position. I guess I needed to learn to ask for and accept help as well as to give it.

SETH Thanks, Alexandra. It’s especially interesting that helping others raised your feeling of self-worth. I wouldn’t have guessed it would have that effect.

Justin Wehr asked me some interview questions and decided not to publish my answers. I thought they were good questions. Here they are, reworded slightly, and my answers.

QUESTION Of the experimental treatments you have studied, which ones have the most positive effect on your life?

ANSWER From more to less effect:

• Effect of morning faces on mood
• Effect of fermented food on health
• (tie) Effect of animal fat on health
• (tie) Effect of omega-3 on health
• Weight-control experiments.

QUESTION What about everyone else?

ANSWER  It depends on how far in the future you look. The morning faces stuff is the most important, I’m sure, but it’s also the hardest to implement. The fermented food stuff is easy to implement. It’s easy to eat more yogurt. So I believe that in the short term, the fermented foods stuff will have the most effect on others, in the long term, the faces stuff.

QUESTION Much of your research is related to the idea that we get sick because we live differently now than long ago. Can you explain this? Are there exceptions?

ANSWER Our genes were shaped to work well in one environment. Now our environment is quite different. All sorts of things go wrong — we don’t eat an optimal diet, for example — and our bodies malfunction in all sorts of ways. The exception is that once we know what an optimal diet (or environment) is we can assure it. For example, we can make sure we get the optimal amount of Vitamin C. The health problems caused by progress can be fixed, in other words, and we can emerge in better shape than ever before.

QUESTION How much time a day do you spend on self-experimentation?

ANSWER About ten minutes. Measuring various things, such as blood pressure and brain function.

QUESTION Why do few people self-experiment?

ANSWER Millions of people self-experiment. For example, millions of fat people try many different ways to lose weight. Professional scientists (e.g., med-school professors) do not self-experiment, at least publicly, because it is low-status, because it is frowned upon (by their colleagues), because it might be hard to publish the results, and because it won’t help them get grants.

QUESTION How do you determine an appropriate dosage for treatments that might have a good effect on what you measure but a bad effect on other things? For example, maybe animal fat is good for sleep but bad for other things.

ANSWER I don’t worry about it. Just as all electric appliances are designed to use the same house current, I’m sure all parts of our body are designed to work best with the same diet.

QUESTION Could advances in medical technologies (such as regenerative medicine) replace the need to live healthily? For example, if we could easily replace livers, maybe people could drink more.

ANSWER Not likely. Except that the more we know about nutrition the more we can replace our ancestors’ diet with a diet made up of the necessary nutrients. For example, I drink flaxseed oil to get omega-3. I’m sure our long-ago ancestors got omega-3 in other ways. So I no longer need to be like them. Basic nutrition isn’t medical technology, but it is a way in which it is easier to be healthy.

QUESTION What don’t you know, but wish you did?

ANSWER How to make book-writing as addictive as Wii Tennis.