Archive for the 'self-experimentation' Category

Self-Experimentation by Anesthesiologists

Saturday, December 13th, 2008

Notes of an Anesthioboist summarizes a long report of events a hundred years ago:

Bier pricked Hildebrandt’s thigh with a needle. Then he passed a blunt, curved needle into the soft tissue of the thigh. No pain.

He pushed a long needle down to the thigh bone a few minutes later. No pain.

A few minutes after that, he applied the burning end of a cigar to Hildebrandt’s legs. (A cigar in the lab…how quaint…)

He pinched a leg (no pain). He pinched the upper chest (lots o’ pain).

He yanked body hairs down below, if you catch my drift (painless - eew). He yanked hairs up high (”very painful”). . .

Both of them subsequently developed debilitating post-dural-puncture headaches that lasted for days (much less common with the finer needles used today).

When is Science Helpful?

Wednesday, December 10th, 2008

Last spring, fourteen Chinese students from elite universities — seven from Tsinghua — traveled to several elite American universities, including Stanford, Harvard, and Yale, under the auspices of a program called IMUSE to discuss sensitive Chinese social topics, such as Tibet or censorship. One of the main events was panel discussions. The American students struck the Chinese students as admirably pragmatic but also in some cases “ignorant and arrogant”.  In response to American students’ criticism, one Chinese student said this: “I eat a lot of rice. My ancestors ate a lot of rice. If you tell me to eat a lot of bread, I don’t know what to eat. I don’t know how to get a healthy diet.”

When I heard that comment, I said it was exactly right. Nutrition is perhaps 75% science, 25% religion. (The discovery of vitamins = science. Thinking the obesity epidemic is due to lack of exercise = religion.) The science part is helpful, the religious part is useless or, if taken seriously, harmful. Nutrition science is too uncertain to choose over the tried and true. Physics is almost 100% science. The stuff in physics textbooks has been used to build lots of useful stuff: buildings, bridges, computers. Economics and political science are perhaps 25% science — too little to rely on their recommendations, which was the Chinese student’s point. Better to rely on tradition. No one tells the American students any of this, however, and they believe far too much of what their professors tell them. (So much for all that teaching how “to think and to reason.”) The result is they give foolish advice.

At Edge, four American experts tried to answer the question “Can science help solve the economic crisis?” Here is a bit of what they said:

Two basic assumptions must guide any thinking as we undertake these tasks. First, economies, financial institutions and markets cannot function without a context of rules and laws, which regulate them. . . . Second, mathematics, physics and computers already play a major and necessary role in our economic affairs.

They believed such statements are helpful. Nassim Taleb responded:

I spent close to 21 years in finance facing “scientists” in some field who show up in finance and economics, realize that economists and practitioners are not as smart as they are (they are not as “rigorous” and did not score as high in math), then think they can figure it all out. Nice, commendable impulse, but I blame the banking crisis (and other blowups) on such “scientism”. . . . Meanwhile the most robust understanding is present among practitioners who do not have the instinct to reduce ambiguity and uncertainty that scientists have.  . . . Please, please, enough of this “science”. We have enough problems without you.

The Chinese student and Taleb are both saying that Big Ideas from elite American universities do not automatically improve on what people elsewhere have done for a long time. Weston Price and Jane Jacobs said the same thing. Somehow elite universities fail to teach this important lesson — perhaps because their professors haven’t learned it.

Thanks to Dave Lull.

Self-Experimentation and Strength Training

Sunday, December 7th, 2008

From Marilia Coutinho, a competitive powerlifter and researcher:

There are two distinct approaches to achieving the “special maximum strength” observed in certain meets: the extreme stress-driven performance, with a lot of screaming, hitting and other means of enhancing alertness and stress response, and the focused approach. The latter is less common.

With the help of a more experienced and accomplished lifter, I came to adopt the focused approach about a year and a half ago. We called it the “white chair thing”. Basically, I spent the moments preceding my turn to lift facing the back of an available white plastic chair, emptying my mind. It is hard to claim this is the one or chief reason why my performance leaped to another level, I broke a couple of national and continental records and visibly improved. There were other factors involved.

After this event, however, I started systematically searching for evidence in the literature. Besides a very old article from decades ago showing competent Olympic lifters performed [more] mental rehearsal of their lifts [than] less competent ones, there was very little published material. The search brought me to martial arts techniques. . . .

I spent one year . . . learning qigong in a tai-chi-chuan program. During this one year, I was frustrated. My performance was irregular, mediocre at competitions and my injuries were a real impediment.

About three weeks after I quit tai-chi-chuan, however, I started applying some qigong techniques in weight training. The results impressed me. I want to create a self-experiment on this and record my results. . . . This might be of great help to many athletes who still believe they need a lot of stress enhancing devices to achieve good marks.

Assorted Links

Sunday, December 7th, 2008

Thanks to Dave Lull and Peter Spero.

Self-Experimentation on Someone Else: Alzheimer’s Disease

Monday, December 1st, 2008

From the St. Petersburg Times:

After two weeks of taking coconut oil, Steve Newport’s results in an early onset Alzheimer’s test gradually improved says his wife, Dr. Mary Newport. Before treatment, Steve could barely remember how to draw a clock. Two weeks after adding coconut oil to his diet, his drawing improved. After 37 days, Steve’s drawing gained even more clarity. [The three drawings are shown in a photo.] The oil seemed to “lift the fog,” his wife says.

. . .

He began taking coconut oil every day, and by the fifth day, there was a tremendous improvement.

The wife took her husband’s treatment into her own hands, just as I tried to improve my sleep myself — it was self-experimentation in that sense.

This is related to my omega-3 research in that it is another example of a fat having highly beneficial brain effects.